Individualized Management for Chronic Diseases of Civilization - Emerging and Future Treatments in Internal Medicine

Wykładowcy / Presenters

Deborah Cook


Deborah Cook practices critical care medicine at St. Joseph’s Healthcare Hamilton. At McMaster University, she is Professor of Medicine, Clinical Epidemiology & Biostatistics and Academic Chair of Critical Care. Her multi-method multi-disciplinary research interests include life support technology, risk factors for critical illness, prevention of ICU-acquired complications, end-of-life choices, and research ethics. Her methodologic work has helped to improve the design, implementation and reporting of randomized trials and systematic reviews. As a Canada Research Chair in Knowledge Translation in Critical Care, and former Chair of the Canadian Critical Care Trials Group, Dr. Cook has published 600 peer-review articles and supervised many trainees and faculty. Dr. Cook has received numerous local, national and international awards for her clinical, educational and research excellence including Fellowship of the Royal Society.


Mark Crowther


Dr. Mark Crowther received his M.D. from the University of Western Ontario in 1990. Between 1995 and 1999 Dr. Crowther undertook a focused Research Fellowship in Thromboembolism under the direction of Drs. Ginsberg, Weitz and Hirsh at McMaster University. Dr. Crowther joined the faculty at McMaster University in 1999 as an Assistant Professor in the Department of Medicine working at St. Joseph's Hospital. Currently, Dr. Crowther is a Professor in the Department of Medicine, Pathology & Molecular Medicine and Clinical Epidemiology & Biostatistics. He also is the Chief, Laboratory Medicine (St. Joseph’s Healthcare and Hamilton Health Sciences Corporation), Vice President of Research (St. Joseph's Healthcare System) and Associate Chair, Department of Medicine, McMaster University. Dr. Crowther's clinical activities focus on the care of patients with thromboembolic disorders, the management of complications of treatments for thromboembolic disorders and other hematologic conditions. Dr. Crowther has presented more than 400 national and international invited talks, published more than 350 peer-reviewed publications, and authored more than 60 book chapters. He holds a Career Investigator award from the Heart and Stroke Foundation of Ontario and the Leo Pharma Chair in Thromboembolism Research at McMaster University.


J. Denburg


Dr Denburg attended McGill University Medical School (1966-8) and Hebrew University, Jerusalem, Israel (1971) where he received his MD. Subsequently, he received his Fellowship Certification (FRCPC) from the Royal College of Physicians and Surgeons of Canada for the specialties of Internal Medicine (1976) and Hematology (1977). Currently, Dr. Denburg is Director and Chief of Service of Clinical Immunology and Allergy at Hamilton Health Sciences, McMaster Division. He is a Professor in the Department of Medicine, Faculty of Health Sciences having received his Professorship in 1988, and holds the William J. Walsh Professorship in General Internal Medicine. Dr. Denburg is active as a physician, with one of the largest practices in Allergy and Immunology in Canada. In his educational role, he serves as the primary link between basic and clinical immunology at McMaster, and has mentored numerous students and fellows into leadership roles in the field of Allergy and Immunology. In addition to his other duties, Dr. Denburg is the Scientific Director and CEO of AllerGen NCE Inc., a Network of Centres of Excellence based at McMaster University whose mandate is to support research, networking, commercialization and capacity building activities that contribute to reducing the morbidity, mortality and socioeconomic impact of allergic disease. Dr. Denburg’s primary research interest is the developmental biology of eosinophils, basophils and mast cells, and their regulation in allergic inflammation and disorders such as mastocytosis and hypereosinophilic syndromes; his pioneering investigations on the systemic nature of allergy has had a profound impact on clinical and basic scientific investigations in the field. Dr Denburg is also a recognized expert on autoimmune diseases such as systemic lupus erythematosus (SLE). Dr. Denburg has received awards for his ongoing peer-reviewed and funded (CIHR, CFI, ODCRF) research, including the Immunology Research Award of the Canadian Society of Allergy and Clinical Immunology (2000), the Burton Zweiman Lectureship, an AAAAI honourary award for outstanding service to the specialty and science of allergy and immunology (2009) and the Jack Hirsh Award for Outstanding Academic Achievement, Department of Medicine, McMaster University (2012). Dr. Denburg has been asked to lead various committees and plan research and educational programmes nationally and internationally. He was elected to the Executive Council of the prestigious Collegium Internationale Allergologicum, and is on the Editorial Board of and/or is primary reviewer for the top journals in the field of Allergy and Immunology globally. His publication list, as well as editorship and/contribution to concept formation and education internationally as an opinion leader in Allergy and Immunology, is extensive with over 300 peer-reviewed scientific journal articles, reviews and book chapters.


P.J. Devereaux


Dr. Devereaux obtained his MD from McMaster University. After medical school he completed a residency in internal medicine at the University of Calgary and a residency in cardiology at Dalhousie University. He then completed a PhD in Clinical Epidemiology at McMaster University. Dr. Devereaux holds a Heart and Stroke Foundation of Ontario Career Investigator Award. He is the Head of Cardiology and the Perioperative Cardiovascular Clinical Program at the Juravinski Hospital and Cancer Centre. He is also the Scientific Leader of the Perioperative Medicine and Surgical Research Group at the Population Health Research Institute. The focus of his clinic research is vascular complications around the time of surgery. He is undertaking several large international RCTs and observational studies addressing this issue. Dr. Devereaux has published over 160 peer reviewed papers and 40 editorials, book chapters, and commentaries.


James Douketis


Dr. James Douketis is Director of Vascular Medicine and Staff Physician in Vascular Medicine and General Internal Medicine at St. Joseph’s Healthcare Hamilton, and Professor of Medicine at McMaster University. He received his Doctor of Medicine degree and completed his residency in Internal Medicine at the University of Toronto. He then completed a thrombosis fellowship at McMaster University. Dr. Douketis’ research interests include: perioperative antithrombotic therapy; prognosis of patients with venous thromboembolism; hormonal therapy and thrombosis; prevention of venous thrombosis in medical patients; and clinical guideline development for the prevention and treatment of obesity. Dr. Douketis is Vice-President of the Thrombosis Canada, Deputy Editor of ACP Journal Club, and has over 200 scientific publications. Dr. Douketis lives in Hamilton with his wife, Dr. Margaret Nowaczyk, a clinical geneticist, and two boys, Jack and Luke, and is a cellist with Symphony-on-the Bay.


Mark Levine


Mark Levine McMaster University, Hamilton, Ontario, Canada Mark Levine is Chair and Professor in the Department of Oncology at McMaster University, Hamilton, Ontario, Canada. He holds the Buffett Taylor Chair in Breast Cancer Research at McMaster University. He is a past recipient of the O. Harold Warwick Prize (1999) from the National Cancer Institute of Canada. Dr. Levine received his medical degree from McGill University, Montreal, Quebec, Canada, and completed his residency in internal medicine at McMaster University. He completed his training in hematology and oncology at Duke University Medical Centre, Durham, North Carolina, USA. In addition, Dr. Levine received a master’s degree in clinical epidemiology and biostatistics from McMaster University. In 1982, Dr. Levine became a member of both the Faculty of Health Sciences at McMaster University, and a medical oncologist at the Hamilton Regional Cancer Centre (now known as the Juravinski Cancer Centre - Hamilton Health Sciences). He was CEO of the Cancer Centre between 1992 and 1999. Over the past 29 years he has been an active researcher in clinical trials and health services research. His focus is in the areas of breast cancer, thromboembolism in malignancy and functional imaging. A number of the trials he has conducted have impacted on health care in both Canada and internationally. He helped establish the Ontario Clinical Oncology Group (OCOG) in 1982 and now is the Director. OCOG is an academic group that designs, coordinates and analyses multicentre trials in cancer. Dr. Levine has over 250 publications in peer-reviewed journals and has brought much research funding to McMaster. He was Chairman of Health Canada’s Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer. Dr. Levine was an Associate Editor of the Journal of Clinical Oncology for seven years and now is a Consultant Editor.


Roman Jaeschke


Dr Jaeschke completed Medical Academy in Kraków, Poland in 1981. In 1982 he received the degree of Doctor of Medicine in Pharmacology from University of Heidelberg in Germany. He subsequently completed training in Internal Medicine at McMaster University in Hamilton, Ontario (1988) and in 1989 received the degree of Master of Science in the Department of Clinical Epidemiology and Biostatistics of the same University. Currently he holds a position of Professor in the Department of Internal Medicine at McMaster University. His clinical work concentrates in the area of general Internal Medicine and Critical Care, and current administrative responsibilities include heading CCRT (critical care response team) at St. Joseph’s Hospital in Hamilton. Dr. Jaeschke’s main academic and teaching interest is in the area of practice guidelines development, quality of life measurement, and various aspects of teaching concepts associated with Evidence Based Medicine. He has over 100 peer reviewed publications and book chapters.


Maciej Małecki


Prof. Maciej Tadeusz Małecki MD, PhD Dr Małecki graduated cum laude from Jagiellonian University Medical College, Krakow, Poland in 1988, later receiving his PhD there in 1998 and being honoured with the Aurelia Baczko Prize for the best doctoral work in Poland the following year. He started his academic career as an assistant resident in internal medicine at the Department of Metabolic Diseases, Jagiellonian University, before spending 3 years (1996–1999) as a research fellow at the Joslin Diabetes Center, Harvard Medical School, in Boston, MA, USA. Dr Małecki returned to the Department of Metabolic Diseases at Jagellonian University as a lecturer, and has been head of the department since 2009. In 2004, he defended his habilitation dissertation, “The molecular background of type 2 diabetes mellitus – pathophysiological and clinical aspects,” and was granted the position of Associate Professor. In 2007, he received the Prime Minister’s Award for Scientific Achievement, going on to become Professor of Medicine in 2009. Dr Małecki is a specialist in internal medicine, diabetology, endocrinology and laboratory diagnostics. He held the post of Vice Dean for Medical Education at Jagiellonian University Medical College (2008–2012), and is currently a Representative of the Rector of the Jagiellonian University for Research and Development at the Medical College. Dr Małecki’s major scientific interest is the genetics of type 2 diabetes mellitus and monogenic forms of the disease, such as MODY (maturity onset diabetes of the young) and permanent neonatal diabetes. He participated in the discovery of the NEUROD1 gene, which is responsible for the MODY6 form of the disease. Other areas of interest include pregnancy complicated by diabetes and new technologies in diabetes care. Dr Małecki has published over 150 original and review papers in respective scientific journals, including Nature Genetics, Nature Clinical Practice Neurology, New England Journal of Medicine, JCI, Diabetes, Diabetologia and Diabetes Care. He serves as a reviewer for the European Commission and several important international journals, as is an associate editor for the European Journal of Clinical Investigation. Dr Małecki has been a Councillor of the European Society for Clinical Investigation (ESCI), and is a member of the European Association for the Study of Diabetes (EASD).


Paul Moayyedi


Dr Paul Moayyedi qualified in medicine from Bristol University and obtained a PhD and Masters in Public Health from the University of Leeds. He was appointed Professor of Gastroenterology at the University of Birmingham in 2001 and then moved to McMaster University to be the first recipient of the Richard Hunt/AstraZeneca Chair of Gastroenterology in 2004. He became Director of the Division of Gastroenterology at McMaster in 2006 and is Acting Director of the Farncombe Family Digestive Health Research Institute since 2012. Dr Paul Moayyedi has published over 250 peer-reviewed articles and 19 book chapters. His work has been cited over 7000 times with an h index of 46. He is a proponent of evidence-based medicine and is the coordinating Editor for the upper GI Cochrane Review Group. He is also co-Editor-in-Chief of the American Journal of Gastroenterology.


Paul M. O'Byrne


Paul M. O’Byrne obtained his Medical Degree at University College, Dublin and his training in Internal Medicine and Respiratory Medicine at McMaster University. He undertook research training under the supervision of Dr. Freddy Hargreave at McMaster University and then Dr. Jay A. Nadel at the Cardiovascular Research Institute in San Francisco. His research interests are on the mechanisms and treatment of asthma with particular reference to the role of environmental allergens and the mechanisms by which these cause airway inflammation. Dr. O’Byrne is currently the E.J. Moran Campbell Professor of Medicine, and Chair of the Department of Medicine at the Michael G DeGroote School of Medicine, McMaster University. He is also the Executive Director of the Firestone Institute for Respiratory Health at St. Joseph’s Healthcare. He has published more than 360 peer reviewed papers, including papers in New England Journal of Medicine, Lancet, Nature Medicine, AJRCCM, JACI and Journal of Immunology. He has authored 90 book chapters, and edited 12 books. He has received the James H Graham Award of Merit, Royal College of Physicians and Surgeons of Canada, and has been the Distinguished Lecturer in Respiratory Sciences for Institute of Circulatory and Respiratory Health of the Canadian Institutes for Health Research. He was elected to the Royal Society of Canada in 2010, and was awarded the European Respiratory Society Congress Award and Medal in 2011. Dr. O’Byrne is the past-Chair of the Executive Committee of the Global Initiative for Asthma (GINA), is Associate Editor of Chest and International Archives of Allergy and Immunology, and is on the Editorial Board of the American Journal of Respirator and Critical Care Medicine and Thorax.


Akbar A. Panju


Dr. Panju graduated from Liverpool Medical School and came to Canada in 1975 and worked as a Family Physician in Northern Ontario, prior to starting Residency in Internal Medicine at McMaster University in 1980. He did further training in Cardiology, Thrombosis and completed course work in Clinical Epidemiology and Biostatistics at McMaster University. His clinical work has been in General Internal Medicine, Cardiology, and Thrombosis at Hamilton Health Sciences Hospitals. He is presently a Professor in the Department of Medicine, McMaster University and Medard DeGroote Chair in General Medicine. He completed a 10 year term as Chief of Medicine at Hamilton Health Sciences in April 2008. He is currently the Division Director of General Internal Medicine at McMaster University and has held this position for the last 15 years. He is also Associate Chair, Clinical Programs at McMaster University. Dr. Panju has been a recipient of Resident Teaching Award, Jack Sibley Award from Faculty of Health Sciences, Sir William Osler Award from Canadian Society of Internal Medicine, and Mentor of the Year Award from The Royal College of Physicians and Surgeons of Canada. Recently he received the Jack Hirsh Award for Academic Excellence from the Department of Medicine, McMaster University. He has been the Past-President of Canadian Society of Internal Medicine and is a member of the Examination Board of Internal Medicine for the Royal College of Physicians and Surgeons of Canada. He is on the Editorial Board for ACP Journal Club and for Evidence-Based Medicine. He has recently co-authored a textbook on Post-Stroke Thalamic Pain. He has published 60 articles in peer-reviewed journals. In 2004, Dr. Panju took over the Medical Director of the Michael G. DeGroote Institute for Pain Research and Care and in that role has been involved in organizing and creating an International Pain Institute at McMaster. His clinical and research interest has been in the management of chronic neuropathic and thalamic pain.


Dan Perri


Dr. Dan Perri is an Associate Professor within the Department of Medicine at McMaster University. His education and training includes degrees in both pharmacy and medicine from the University of Toronto and Royal College of Physicians and Surgeons of Canada accredited training in internal medicine, clinical pharmacology and toxicology, and critical care medicine undertaken at McMaster University and the University of Toronto. He has also completed a medication safety fellowship with the Institute for Medication Safety and continues to provide medication safety consultations for the Institute for Safe Medication Practices (ISMP) Canada. He practices general internal medicine and critical care medicine at St. Joseph's Healthcare Hamilton and provides consultations in clinical pharmacology and toxicology. His research interests include medication safety and the appropriate use of medications for critically ill patients. He has published journal articles, textbook chapters, and co-authored or edited a variety of works covering a broad range of topics in clinical pharmacology, teratology, and toxicology for both prescription medicines and natural health products. He is an editorial board member for several in-print and on-line clinical pharmacology and therapeutics journals, is active in simulation-based patient safety education, and is developing a knowledge transfer toolkit for improved ICU medication safety.


Christine Ribic


Dr. Christine Ribic is a transplant nephrologist and an assistant professor at McMaster University. She obtained her MD from the University of Toronto and completed her Internal Medicine and Nephrology residency at McMaster University. She completed a Master of Science in Pharmacology at the University of Toronto in 2001 and is currently completing a second Master of Science in Clinical Epidemiology and Biostatistics in the Health Research Methodology Program at McMaster University. Dr. Ribic’s research interests are in the area of renal transplantation and end stage renal disease with a focus on disease prevention and health outcomes utilizing both clinical studies as well as large national databases. She is currently the principal investigator on a prospective, observational cohort study examining venous thromboembolism in recipients of renal transplants in addition to several other research projects in transplant recipients and patients with end stage renal disease.


Robert Sheppard


Biography Dr. Robert Sheppard, MD, BCEM (AAPS) Dr. Sheppard completed undergraduate degrees in Physical Education and Sociology from McMaster University, Hamilton in 1975, then pursued Masters’ education in Theology at Fuller Theological School, UCLA. From 1975-1982, he developed and worked in a charitable organization for both troubled and gifted adolescents. He also worked as a high school athletic coach in Pittsburgh, Pa and Hamilton,Ontario. In 1985, he completed his MD at McMaster University, followed by residency training in Internal Medicine and Psychiatry. An Emergency Medicine locum in Orillia, Ontario initiated his subsequent career in acute care medicine. During the first 5 years in this underserviced area, he also had a private family practice including obstetrics. In 1991, Dr. Sheppard relocated to Texas to pursue his Emergency Medicine career, where he continues to practice today at North Cypress Medical Center and is Chair of the Department of Emergency Services. During his career, Dr. Sheppard has been Chair of 4 Emergency Departments, Assistant Professor of Emergency Medicine at the University of Texas Medical Branch, Chief of Staff of Cypress Fairbanks Hospital, and Past President of the Medical Staff at North Cypress Medical Center. Solving health care access problems with ‘out of the box’ thinking has been Dr. Sheppard’s passion. This is reflected in his founding the After Hours Urgent Care Clinic in Orillia, Ontario, co- developing a hospital in Tegucigalpa, Honduras, and founding and co-developing North Cypress Medical Center in Houston, Texas. Dr. Sheppard is President and Managing Partner of Cypress Emergency Associates, a team of 30 Emergency physicians staffing the 3 Emergency Departments of North Cypress Medical Center where he is also a Member of the Board of Governors.


Agnieszka Słowik


Dr Agnieszka Słowik is a Professor of Neurology at Jagiellonian University Krakow, Poland. Her research is focuses on understanding stroke through clinical and genetic approaches. She collaborates broadly with the stroke genetics community in conducting research in the neurogenetics of cerebral stroke. Her other research interests include ALS and Alzheimer's disease.


Wojciech Szczeklik


Dr. Wojciech Szczeklik received his Doctor of Medicine degree from Jagiellonian University Medical College. After medical school he completed residency in Internal Medicine and Critical Care, and received PhD at Jagiellonian University Medical College. His foreign clinical and research experience include University College in London, Harvard University, University of Cambridge and McMaster University. The focus of his research are autoimmune diseases, critical care, and vascular complications around the time of noncardiac surgery. Dr. Szczeklik has published more than 50 peer-reviewed publication, and authored more than 30 book chapters. He received several awards for young researchers. Dr. Wojciech Szczeklik currently holds a position of Associate Professor within the Department of Medicine at the Jagiellonian University Medical College.